This course aims to equip students with the knowledge, skills, and mindset to apply design thinking methodologies to solve real-world health informatics challenges. By the end of the course, students will have a deep understanding of the principles and process of design thinking and how it can be applied to health informatics. They will develop skills in user-centered design, including techniques for conducting user research, prototyping, and user testing. Students will apply design thinking methodologies to real-world health informatics challenges and develop innovative solutions that meet the needs of stakeholders and end-users.